Intracellular delivery of messenger RNA to macrophages with surfactant-derived lipid nanoparticles

The broad biomedical applications of messenger RNA (mRNA)-based therapeutics rely heavily on the rapid development of mRNA delivery systems. In this study, dual-component lipid nanoparticles (LNPs) were developed for intracellular delivery of mRNA to macrophages. By screening a panel of quaternary a...

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Bibliographic Details
Main Authors: Y. Huang, M. Yang, N. Wang, S. Li, Z. Liu, Z. Li, Z. Ji, B. Li
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Materials Today Advances
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590049822000911