Renal failure suppresses muscle irisin expression, and irisin blunts cortical bone loss in mice
Abstract Background Chronic renal failure induces bone mineral disorders and sarcopenia. Skeletal muscle affects other tissues, including bone, by releasing myokines. However, the effects of chronic renal failure on the interactions between muscle and bone remain unclear. Methods We investigated the...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-02-01
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Series: | Journal of Cachexia, Sarcopenia and Muscle |
Subjects: | |
Online Access: | https://doi.org/10.1002/jcsm.12892 |