Host-defense piscidin peptides as antibiotic adjuvants against Clostridioides difficile.

Host-defense piscidin peptides as antibiotic adjuvants against Clostridioides difficile.

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The spore-forming intestinal pathogen Clostridioides difficile causes multidrug resistant infection with a high rate of recurrence after treatment. Piscidins 1 (p1) and 3 (p3), cationic host defense peptides with micromolar cytotoxicity against C. difficile, sensitize C. difficile to clinically rele...

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Bibliographic Details
Main Authors: Adenrele Oludiran, Areej Malik, Andriana C Zourou, Yonghan Wu, Steven P Gross, Albert Siryapon, Asia Poudel, Kwincy Alleyne, Savion Adams, David S Courson, Myriam L Cotten, Erin B Purcell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295627&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295627&type=printable

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