Genetic correlation of the plasma lipidome with type 2 diabetes, prediabetes and insulin resistance in Mexican American families

Genetic correlation of the plasma lipidome with type 2 diabetes, prediabetes and insulin resistance in Mexican American families

Abstract Background Differential plasma concentrations of circulating lipid species are associated with pathogenesis of type 2 diabetes (T2D). Whether the wide inter-individual variability in the plasma lipidome contributes to the genetic basis of T2D is unknown. Here, we investigated the potential...

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Bibliographic Details
Main Authors: Hemant Kulkarni, Manju Mamtani, Gerard Wong, Jacquelyn M. Weir, Christopher K. Barlow, Thomas D. Dyer, Laura Almasy, Michael C. Mahaney, Anthony G. Comuzzie, Ravindranath Duggirala, Peter J. Meikle, John Blangero, Joanne E. Curran
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Genetics
Subjects:
Type 2 diabetes
Plasma lipidome
Genetic correlation
Bivariate trait analyses
Family studies
Online Access:http://link.springer.com/article/10.1186/s12863-017-0515-5

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http://link.springer.com/article/10.1186/s12863-017-0515-5

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