The cytotoxic action of BCI is not dependent on its stated DUSP1 or DUSP6 targets in neuroblastoma cells

Neuroblastoma (NB) is a heterogeneous cancer of the sympathetic nervous system, which accounts for 7–10% of paediatric malignancies worldwide. Due to the lack of targetable molecular aberrations in NB, most treatment options remain relatively nonspecific. Here, we investigated the therapeutic potent...

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Bibliographic Details
Main Authors: Elliott M. Thompson, Vruti Patel, Vinothini Rajeeve, Pedro R Cutillas, Andrew W. Stoker
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13418