Long non-coding RNA BZRAP1-AS1 silencing suppresses tumor angiogenesis in hepatocellular carcinoma by mediating THBS1 methylation

Long non-coding RNA BZRAP1-AS1 silencing suppresses tumor angiogenesis in hepatocellular carcinoma by mediating THBS1 methylation

Abstract Background Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer associated with a high mortality. Long non-coding RNAs (lncRNAs) have recently emerged as regulators in the development and progression of several cancers, and therefore represent an opportunity to uncover n...

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Bibliographic Details
Main Authors: Weiwei Wang, Guoyong Chen, Bing Wang, Zhenhua Yuan, Guangbo Liu, Biao Niu, Yongfeng Chen, Shaotang Zhou, Junchuang He, Huanzhou Xue
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Translational Medicine
Subjects:
Hepatocellular carcinoma
Long non-coding RNA
BZRAP1-AS1
DNA methyltransferase 3B
Thrombospondin-1
DNA methylation
Online Access:https://doi.org/10.1186/s12967-019-02145-6

Internet

https://doi.org/10.1186/s12967-019-02145-6

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