The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium

Abstract The efficient transport of proteins into the primary cilium is a crucial step for many signaling pathways. Dysfunction of this process can lead to the disruption of signaling cascades or cilium assembly, resulting in developmental disorders and cancer. Previous studies on the protein delive...

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Bibliographic Details
Main Authors: S. M. Niedziółka, S. Datta, T. Uśpieński, B. Baran, W. Skarżyńska, E. W. Humke, R. Rohatgi, P. Niewiadomski
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-05817-2