The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium
Abstract The efficient transport of proteins into the primary cilium is a crucial step for many signaling pathways. Dysfunction of this process can lead to the disruption of signaling cascades or cilium assembly, resulting in developmental disorders and cancer. Previous studies on the protein delive...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-02-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-024-05817-2 |