Less Severe Sepsis in Cecal Ligation and Puncture Models with and without Lipopolysaccharide in Mice with Conditional <i>Ezh2</i>-Deleted Macrophages (LysM-Cre System)

Less Severe Sepsis in Cecal Ligation and Puncture Models with and without Lipopolysaccharide in Mice with Conditional <i>Ezh2</i>-Deleted Macrophages (LysM-Cre System)

Despite a previous report on less inflammatory responses in mice with an absence of the enhancer of zeste homologue 2 (Ezh2), a histone lysine methyltransferase of epigenetic regulation, using a lipopolysaccharide (LPS) injection model, proteomic analysis and cecal ligation and puncture (CLP), a sep...

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Bibliographic Details
Main Authors: Pornpimol Phuengmaung, Phuriwat Khiewkamrop, Jiradej Makjaroen, Jiraphorn Issara-Amphorn, Atsadang Boonmee, Salisa Benjaskulluecha, Patcharee Ritprajak, Aleksandra Nita-Lazar, Tanapat Palaga, Nattiya Hirankarn, Asada Leelahavanichkul
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
sepsis
lipopolysaccharide
macrophages
epigenetics
Ezh2
Online Access:https://www.mdpi.com/1422-0067/24/10/8517

Internet

https://www.mdpi.com/1422-0067/24/10/8517

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