Insights into the heterogeneity of iNKT cells: tissue-resident and circulating subsets shaped by local microenvironmental cues

Insights into the heterogeneity of iNKT cells: tissue-resident and circulating subsets shaped by local microenvironmental cues

Invariant natural killer T (iNKT) cells are a distinct subpopulation of innate-like T lymphocytes. They are characterized by semi-invariant T cell receptors (TCRs) that recognize both self and foreign lipid antigens presented by CD1d, a non-polymorphic MHC class I-like molecule. iNKT cells play a cr...

Full description

Bibliographic Details
Main Authors: Guangwei Cui, Shinya Abe, Ryoma Kato, Koichi Ikuta
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
iNKT cell
heterogeneity
immune microenvironment
IL-15
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1349184/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1349184/full

Similar Items