Transcriptomic and Proteomic Analysis of CRISPR/Cas9-Mediated <i>ARC</i>-Knockout HEK293 Cells

Arc/Arg3.1 (activity-regulated cytoskeletal-associated protein (ARC)) is a critical regulator of long-term synaptic plasticity and is involved in the pathophysiology of schizophrenia. The functions and mechanisms of human ARC action are poorly understood and worthy of further investigation. To inves...

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Bibliographic Details
Main Authors: Yu-Yuan Wang, Shih-Hsin Hsu, Hsin-Yao Tsai, Fu-Yu Cheng, Min-Chih Cheng
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/9/4498