Functional Blockage of S100A8/A9 Ameliorates Ischemia–Reperfusion Injury in the Lung

Functional Blockage of S100A8/A9 Ameliorates Ischemia–Reperfusion Injury in the Lung

(1) Background: Lung ischemia–reperfusion (IR) injury increases the mortality and morbidity of patients undergoing lung transplantation. The objective of this study was to identify the key initiator of lung IR injury and to evaluate pharmacological therapeutic approaches using a functional inhibitor...

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Bibliographic Details
Main Authors: Kentaro Nakata, Mikio Okazaki, Tomohisa Sakaue, Rie Kinoshita, Yuhei Komoda, Dai Shimizu, Haruchika Yamamoto, Shin Tanaka, Ken Suzawa, Kazuhiko Shien, Kentaroh Miyoshi, Hiromasa Yamamoto, Toshiaki Ohara, Seiichiro Sugimoto, Masaomi Yamane, Akihiro Matsukawa, Masakiyo Sakaguchi, Shinichi Toyooka
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Bioengineering
Subjects:
ischemia reperfusion injury
S100A8/A9
lung transplantation
damage-associated molecule patterns
Online Access:https://www.mdpi.com/2306-5354/9/11/673

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https://www.mdpi.com/2306-5354/9/11/673

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