In Silico Study of Different Thrombolytic Agents for Fibrinolysis in Acute Ischemic Stroke

Alteplase is the only FDA-approved drug for thrombolysis in acute ischemic stroke (AIS). Meanwhile, several thrombolytic drugs are deemed to be promising candidates to substitute alteplase. This paper evaluates the efficacy and safety of urokinase, ateplase, tenecteplase, and reteplase for intraveno...

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Bibliographic Details
Main Authors: Yilin Yang, Boram Gu, Xiao Yun Xu
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/3/797