Transgenic LRRK2R1441G rats–a model for Parkinson disease?

Parkinson disease (PD) is the most common movement disorder, characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra. While the cause of this disease is largely unknown, a rare autosomal dominant familial form of PD is caused by a genetic mutation in the leucine...

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Bibliographic Details
Main Authors: Komal T. Shaikh, Alvin Yang, Ekaterina Youshin, Susanne Schmid
Format: Article
Language:English
Published: PeerJ Inc. 2015-05-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/945.pdf