Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents

Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents

Abstract Reduced knee weight-bearing from prescription or sedentary lifestyles are associated with cartilage degradation; effects on the meniscus are unclear. Rodents exposed to spaceflight or hind limb unloading (HLU) represent unique opportunities to evaluate this question. This study evaluated ar...

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Bibliographic Details
Main Authors: Andy T. Kwok, Nequesha S. Mohamed, Johannes F. Plate, Raghunatha R. Yammani, Samuel Rosas, Ted A. Bateman, Eric Livingston, Joseph E. Moore, Bethany A. Kerr, Jingyun Lee, Cristina M. Furdui, Li Tan, Mary L. Bouxsein, Virginia L. Ferguson, Louis S. Stodieck, David C. Zawieja, Michael D. Delp, Xiao W. Mao, Jeffrey S. Willey
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90010-2

Internet

https://doi.org/10.1038/s41598-021-90010-2

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