mRNA alternative polyadenylation (APA) in regulation of gene expression and diseases

The mRNA polyadenylation plays essential function in regulation of mRNA metabolism. Mis-regulations of mRNA polyadenylation are frequently linked with aberrant gene expression and disease progression. Under the action of polyadenylate polymerase, poly(A) tail is synthesized after the polyadenylation...

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Bibliographic Details
Main Authors: Siyao Guo, Shuibin Lin
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-01-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304221001136