Human Caspase 12 Enhances NF-κB Activity through Activation of IKK in Nasopharyngeal Carcinoma Cells

Human Caspase 12 Enhances NF-κB Activity through Activation of IKK in Nasopharyngeal Carcinoma Cells

Human nasopharyngeal carcinoma (NPC) is a highly invasive cancer associated with proinflammation. Caspase-12 (Casp12), an inflammatory caspase, is implicated in the regulation of NF-κB-mediated cellular invasion via the modulation of the IκBα protein in NPC cells. However, the effect mechanisms of C...

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Bibliographic Details
Main Authors: Shu-Er Chow, Huei-Tzu Chien, Wing-Keung Chu, Victor Lin, Tzu-Hsiu Shen, Shiang-Fu Huang
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
Caspase-12
inflammation
IKK
IκBα
NF-κB
human nasopharyngeal carcinoma
Online Access:https://www.mdpi.com/1422-0067/22/9/4610

Internet

https://www.mdpi.com/1422-0067/22/9/4610

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