Multivariate chemogenomic screening prioritizes new macrofilaricidal leads
A comprehensive optimization of phenotypic and computational screening strategy for antifilarial drug and target discovery identifies compounds with stage, species, and/or sex-specific activity, some with submicromolar potency.
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04435-8 |