Homogenous subpopulation of human mesenchymal stem cells and their extracellular vesicles restore function of endometrium in an experimental rat model of Asherman syndrome

Homogenous subpopulation of human mesenchymal stem cells and their extracellular vesicles restore function of endometrium in an experimental rat model of Asherman syndrome

Abstract Background Asherman syndrome (AS), or intrauterine adhesions, is a main cause of infertility in reproductive age women after endometrial injury. Mesenchymal stem cells (MSCs) and their extracellular vesicles (EVs) are promising candidates for therapies that repair damaged endometria. Howeve...

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Bibliographic Details
Main Authors: Nahid Mansouri-Kivaj, Abdoreza Nazari, Fereshteh Esfandiari, Faezeh Shekari, Marefat Ghaffari, Mohammad Pakzad, Hossein Baharvand
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Stem Cell Research & Therapy
Subjects:
Asherman syndrome
Stem cell therapy
Clonal mesenchymal stem cells
Extracellular vesicles
Subpopulation
Online Access:https://doi.org/10.1186/s13287-023-03279-7

Internet

https://doi.org/10.1186/s13287-023-03279-7

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