A theory-based practical solution to correct for sex-differential participation bias

Abstract Most genomic cohorts are retrospective where the exposures and outcomes are predetermined prior to sample collection. Therefore, a spurious association between an exposure and an outcome can arise if both variables affect study participation. Such concerns were raised in previous studies qu...

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Bibliographic Details
Main Authors: Hanbin Lee, Buhm Han
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-022-02703-0