Fgf signalling triggers an intrinsic mesodermal timer that determines the duration of limb patterning

Fgf signalling triggers an intrinsic mesodermal timer that determines the duration of limb patterning

Abstract Complex signalling between the apical ectodermal ridge (AER - a thickening of the distal epithelium) and the mesoderm controls limb patterning along the proximo-distal axis (humerus to digits). However, the essential in vivo requirement for AER-Fgf signalling makes it difficult to understan...

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Bibliographic Details
Main Authors: Sofia Sedas Perez, Caitlin McQueen, Holly Stainton, Joseph Pickering, Kavitha Chinnaiya, Patricia Saiz-Lopez, Marysia Placzek, Maria A. Ros, Matthew Towers
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41457-6

Internet

https://doi.org/10.1038/s41467-023-41457-6

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