The efficacy and safety of short-course radiotherapy followed by sequential chemotherapy and Cadonilimab for locally advanced rectal cancer: a protocol of a phase II study

The efficacy and safety of short-course radiotherapy followed by sequential chemotherapy and Cadonilimab for locally advanced rectal cancer: a protocol of a phase II study

Abstract Background For patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment through the integration of radiotherapy and systemic chemotherapy before surgery, was commonly recommended as the standard treatment. However, the...

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Bibliographic Details
Main Authors: Tongzhen Xu, Lingling Feng, Wenjue Zhang, Haoyue Li, Huiying Ma, Muyasha Abulimiti, Yutong Tan, Feiyan Deng, Wenting Huang, Shuangmei Zou, Wenyan Kang, Liming Jiang, Ying Wang, Chen Hu, Yinggang Chen, Haitao Zhou, Yuan Tang, Jing Jin
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Cancer
Subjects:
Locally advanced rectal cancer
Bispecific antibody immunotherapy
Short-course radiotherapy
Total neoadjuvant therapy
Complete response
Online Access:https://doi.org/10.1186/s12885-024-12254-1

Internet

https://doi.org/10.1186/s12885-024-12254-1

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