Impact of Gold Nanoparticles on Testosterone Metabolism in Human Liver Microsomes

Impact of Gold Nanoparticles on Testosterone Metabolism in Human Liver Microsomes

Abstract Gold nanoparticle (AuNP)-protein corona complexes can alter cytochrome P450 (CYP)-mediated testosterone (TST) metabolism by altering their physicochemical properties. We investigated the impact of NP size, surface chemistry, and protein corona in TST metabolism in pooled human liver microso...

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Bibliographic Details
Main Authors: Kyoungju Choi, Hyun Joo
Format: Article
Language:English
Published: SpringerOpen 2019-06-01
Series:Nanoscale Research Letters
Subjects:
Gold nanoparticles
Human plasma protein corona
Testosterone metabolism
Human liver microsomes
Cytochrome P450
Individual variation
Online Access:http://link.springer.com/article/10.1186/s11671-019-3021-z

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http://link.springer.com/article/10.1186/s11671-019-3021-z

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