Prediction of post-PCV13 pneumococcal evolution using invasive disease data enhanced by inverse-invasiveness weighting

Prediction of post-PCV13 pneumococcal evolution using invasive disease data enhanced by inverse-invasiveness weighting

ABSTRACT After introducing pneumococcal conjugate vaccines (PCVs), serotype replacement occurred in Streptococcus pneumoniae. Predicting which pneumococcal strains will become common in carriage after vaccination can enhance vaccine design, public health interventions, and understanding of pneumococ...

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Bibliographic Details
Main Authors: Xueting Qiu, Lesley McGee, Laura L Hammitt, Lindsay R. Grant, Katherine L. O’Brien, William P. Hanage, Marc Lipsitch
Format: Article
Language:English
Published: American Society for Microbiology 2024-10-01
Series:mBio
Subjects:
Streptococcus pneumoniae
invasive disease surveillance data
inverse-invasiveness weighting
carriage population
negative frequency-dependent selection
Online Access:https://journals.asm.org/doi/10.1128/mbio.03355-23

Internet

https://journals.asm.org/doi/10.1128/mbio.03355-23

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