Expression of CXCL12-CXCR4/CXCR7 chemokines in splenic fibrosis of cirrhotic spleen and its therapeutic significance

Introduction To investigate the expression and treatment of chemokine CXCL12 and its receptor CXCR4/CXCR7. Methods The liver cirrhosis hypersplenism model of rats was made with CCL4, and then was detected by immunohistochemistry, Western blot and qRT-PCR. Results The area of spleen fibrosis in the...

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Bibliographic Details
Main Authors: Yunfu Lv, Yejuan Li, XiaoYu Han, Ning Liu, Min Zeng
Format: Article
Language:English
Published: Termedia Publishing House 2023-08-01
Series:Archives of Medical Science
Subjects:
Online Access:https://www.archivesofmedicalscience.com/Expression-of-CXCL12-CXCR4-CXCR7-chemokines-in-splenic-fibrosis-of-cirrhotic-spleen,170910,0,2.html