Generalized Additive Mixed-Models for Pharmacology Using Integrated Discrete Multiple Organ Co-Culture.

Generalized Additive Mixed-Models for Pharmacology Using Integrated Discrete Multiple Organ Co-Culture.

Integrated Discrete Multiple Organ Co-culture (IDMOC) is emerging as an in-vitro alternative to in-vivo animal models for pharmacology studies. IDMOC allows dose-response relationships to be investigated at the tissue and organoid levels, yet, these relationships often exhibit responses that are far...

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Bibliographic Details
Main Authors: Thomas Ingersoll, Stephanie Cole, Janna Madren-Whalley, Lamont Booker, Russell Dorsey, Albert Li, Harry Salem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4844122?pdf=render

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http://europepmc.org/articles/PMC4844122?pdf=render

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