The effective use of blebbistatin to study the action potential of cardiac pacemaker cells of zebrafish (Danio rerio) during incremental warming

Blebbistatin potently inhibits actin-myosin interaction, preventing contractile activity of excitable cells including cardiac myocytes, despite electrical excitation of an action potential (AP). We collected intracellular microelectrode recordings of pacemaker cells located in the sinoatrial region...

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Bibliographic Details
Main Authors: L. Marchant James, M. Smith Frank, P. Farrell Anthony
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Physiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665944122000025