Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety

Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety

<p>Abstract</p> <p>Background</p> <p>Hepatocyte growth factor (HGF) stimulates hepatocyte proliferation, and also acts as an anti-apoptotic factor. Therefore, HGF is a potential therapeutic agent for treatment of fatal liver diseases. We performed a translational medici...

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Bibliographic Details
Main Authors: Setoyama Hitoshi, Yamaji Naohisa, Marusawa Hiroyuki, Teramukai Satoshi, Murayama Toshinori, Numata Masatsugu, Moriuchi Akihiro, Ido Akio, Kim Il-Deok, Chiba Tsutomu, Higuchi Shuji, Yokode Masayuki, Fukushima Masanori, Shimizu Akira, Tsubouchi Hirohito
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/55

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http://www.translational-medicine.com/content/9/1/55

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