Proinflammatory intervertebral disc cell and organ culture models induced by tumor necrosis factor alpha
Abstract Inflammation plays an important role in the pathogenesis of intervertebral disc (IVD) degeneration. The proinflammatory cytokine tumor necrosis factor alpha (TNF‐α) has shown markedly higher expression in degenerated human disc tissue compared with healthy controls. Anti‐inflammatory treatm...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-09-01
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Series: | JOR Spine |
Subjects: | |
Online Access: | https://doi.org/10.1002/jsp2.1104 |