Synthesis of zearalenone-16-β,D-glucoside and zearalenone-16-sulfate: A tale of protecting resorcylic acid lactones for regiocontrolled conjugation

The development of a reliable procedure for the synthesis of the 16-glucoside and 16-sulfate of the resorcylic acid lactone (RAL) type compound zearalenone is presented. Different protective group strategies were considered and applied to enable the preparation of glucosides and sulfates that are di...

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Bibliographic Details
Main Authors: Hannes Mikula, Julia Weber, Dennis Svatunek, Philipp Skrinjar, Gerhard Adam, Rudolf Krska, Christian Hametner, Johannes Fröhlich
Format: Article
Language:English
Published: Beilstein-Institut 2014-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.10.112