A protein–protein interaction map reveals that the Coxiella burnetii effector CirB inhibits host proteasome activity

A protein–protein interaction map reveals that the Coxiella burnetii effector CirB inhibits host proteasome activity

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Coxiella burnetii is the etiological agent of the zoonotic disease Q fever, which is featured by its ability to replicate in acid vacuoles resembling the lysosomal network. One key virulence determinant of C. burnetii is the Dot/Icm system that transfers more than 150 effector proteins into host cel...

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Bibliographic Details
Main Authors: Mengjiao Fu, Yuchen Liu, Guannan Wang, Peng Wang, Jianing Zhang, Chen Chen, Mingliang Zhao, Shan Zhang, Jun Jiao, Xuan Ouyang, Yonghui Yu, Bohai Wen, Chengzhi He, Jian Wang, Dongsheng Zhou, Xiaolu Xiong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273094/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273094/?tool=EBI

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