The size and composition of haplotype reference panels impact the accuracy of imputation from low-pass sequencing in cattle

Abstract Background Low-pass sequencing followed by sequence variant genotype imputation is an alternative to the routine microarray-based genotyping in cattle. However, the impact of haplotype reference panels and their interplay with the coverage of low-pass whole-genome sequencing data have not b...

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Bibliographic Details
Main Authors: Audald Lloret-Villas, Hubert Pausch, Alexander S. Leonard
Format: Article
Language:deu
Published: BMC 2023-05-01
Series:Genetics Selection Evolution
Online Access:https://doi.org/10.1186/s12711-023-00809-y