Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Aquaporin Superfamily (Superaquaporins): Expansion of Aquaporins Restricted to Multicellular Organisms

Eleven aquaporins are identified in mammals. They all have highly conserved two asparagine-proline-alanine (NPA) boxes that are important for the formation of the water permeating pore. Recently we identified two new proteins in mammals distantly related to aquaporins (AQPs) with poorly conserved NP...

Full description

Bibliographic Details
Main Authors: Yoshiyuki Morishita, Yasuji Sakube, Sei Sasaki, Kenichi Ishibashi
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319323394