Gosha-Jinki-Gan Improved Erectile Dysfunction Caused by Anti-Cancer Agent Oxaliplatin by Decreasing Transcriptional Expression of Phosphodiesterase-5 in Rats

Gosha-Jinki-Gan Improved Erectile Dysfunction Caused by Anti-Cancer Agent Oxaliplatin by Decreasing Transcriptional Expression of Phosphodiesterase-5 in Rats

ABSTRACT: Background: A platinum-containing anti-cancer agent, oxaliplatin (L-OHP), is known to induce peripheral neuropathy, including erectile dysfunction (ED) as a side effect, while Gosha-jinki-gan (GJG) is a traditional Japanese herbal medicine mainly used for peripheral neuropathy. Aim: To in...

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Bibliographic Details
Main Authors: Tomoya Kataoka, PhD, Yuto Kawaki, Yohei Kito, Jun Suzuki, Taiki Mori, Yuji Hotta, PhD, Akimasa Sanagawa, PhD, Yoshihiro Kawade, Yasuhiro Maeda, PhD, Yoko Furukawa-Hibi, PhD, Kazunori Kimura, PhD
Format: Article
Language:English
Published: Oxford University Press 2022-04-01
Series:Sexual Medicine
Subjects:
Gosha-Jinki-Gan
Anticancer Agents
Erectile Dysfunction
Phosphodiesterase-5
Online Access:http://www.sciencedirect.com/science/article/pii/S2050116121001641

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http://www.sciencedirect.com/science/article/pii/S2050116121001641

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