Branched-Chain Amino Acids Are Linked with Alzheimer’s Disease-Related Pathology and Cognitive Deficits

Branched-Chain Amino Acids Are Linked with Alzheimer’s Disease-Related Pathology and Cognitive Deficits

Alzheimer’s disease (AD) is an irreversible neurodegenerative disorder with a complex pathophysiology. Type 2 diabetes (T2D) is a strong risk factor for AD that shares similar abnormal features including metabolic dysregulation and brain pathology such as amyloid and/or Tau deposits. Emerging eviden...

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Bibliographic Details
Main Authors: Md Abu Bakkar Siddik, Caitlyn A. Mullins, Alyssa Kramer, Harsh Shah, Ritchel B. Gannaban, Masoud Zabet-Moghaddam, Ryan M. Huebinger, Vijay K. Hegde, Sheba M. J. MohanKumar, Puliyur S. MohanKumar, Andrew C. Shin
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
glucose metabolism
BCAA
neurotransmitters
Aβ-42
Tau
5xFAD
Online Access:https://www.mdpi.com/2073-4409/11/21/3523

Internet

https://www.mdpi.com/2073-4409/11/21/3523

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