MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway

MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway

Abstract Sleep deprivation (SD) can lead to cognitive impairment caused by neuroinflammation. MiR-181c-5p/HMGB1 axis plays a part in anti-inflammation effects. However, the mechanism that miR-181c-5p facilitates learning and memory in SD mice remains unclear. So we investigated the role of miR-181c-...

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Bibliographic Details
Main Authors: YUJIE HU, CHONG HU, JIERONG YIN, JIALING ZHONG, YUAN DENG, GUOSHUAI YANG
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2023-07-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
sleep deprivation
miR-181c-5p
learning-memory ability
HMGB1/TLR4/NF-Κb
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652023000200605&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652023000200605&tlng=en

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