Gut microbiota of old mice worsens neurological outcome after brain ischemia via increased valeric acid and IL-17 in the blood
Abstract Background Aging is a significant risk factor for ischemic stroke and worsens its outcome. However, the mechanisms for this worsened neurological outcome with aging are not clearly defined. Results Old C57BL/6J male mice (18 to 20 months old) had a poorer neurological outcome and more sever...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-09-01
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Series: | Microbiome |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40168-023-01648-1 |