Data integration across conditions improves turnover number estimates and metabolic predictions
The construction of protein-constrained genome-scale metabolic models depends on the integration of organism-specific enzyme turnover numbers. Here, the authors show that correction of turnover numbers by simultaneous consideration of proteomics and physiological data leads to improved predictions o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-37151-2 |