Clonal Analysis of Gliogenesis in the Cerebral Cortex Reveals Stochastic Expansion of Glia and Cell Autonomous Responses to Egfr Dosage

Clonal Analysis of Gliogenesis in the Cerebral Cortex Reveals Stochastic Expansion of Glia and Cell Autonomous Responses to Egfr Dosage

Development of the nervous system undergoes important transitions, including one from neurogenesis to gliogenesis which occurs late during embryonic gestation. Here we report on clonal analysis of gliogenesis in mice using Mosaic Analysis with Double Markers (MADM) with quantitative and computationa...

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Bibliographic Details
Main Authors: Xuying Zhang, Christine V. Mennicke, Guanxi Xiao, Robert Beattie, Mansoor A. Haider, Simon Hippenmeyer, H. Troy Ghashghaei
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
cerebral cortex
clonal analysis
neurogenesis
gliogenesis
Egfr
astrocyte
Online Access:https://www.mdpi.com/2073-4409/9/12/2662

Internet

https://www.mdpi.com/2073-4409/9/12/2662

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