Elevated E200K Somatic Mutation of the Prion Protein Gene (<i>PRNP</i>) in the Brain Tissues of Patients with Sporadic Creutzfeldt–Jakob Disease (CJD)
Sporadic Creutzfeldt–Jakob disease (CJD) is a major human prion disease worldwide. CJD is a fatal neurodegenerative disease caused by an abnormal prion protein (PrP<sup>Sc</sup>). To date, the exact etiology of sporadic CJD has not been fully elucidated. We investigated the E200K and V20...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-10-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/24/19/14831 |