Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells
<p>Abstract</p> <p>Background</p> <p>Drug resistance is a major concern in cancer therapy. Here, we investigate the clinical potential of the second mitochondria-derived activator of caspase (Smac/DIABLO) in enhancing the apoptosis-inducing potential of commonly used an...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2008-06-01
|
Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/7/1/60 |