Dissecting the DNA binding landscape and gene regulatory network of p63 and p53
The transcription factor p53 is the best-known tumor suppressor, but its sibling p63 is a master regulator of epidermis development and a key oncogenic driver in squamous cell carcinomas (SCC). Despite multiple gene expression studies becoming available, the limited overlap of reported p63-dependent...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/63266 |