Endogenous AJAP1 associates with the cytoskeleton and attenuates angiogenesis in endothelial cells

The adherens junction associated protein 1 (AJAP1, aka shrew-1) is presumably a type-I transmembrane protein localizing and interacting with the E-cadherin-catenin complex. In various tumors, AJAP1 expression is reduced or lost, including hepatocellular and esophageal squamous cell carcinoma, and gl...

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Bibliographic Details
Main Authors: Katharina Hötte, Isabell Smyrek, Anna Starzinski-Powitz, Ernst H. K. Stelzer
Format: Article
Language:English
Published: The Company of Biologists 2017-06-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/6/6/723