Novel insights into the role of acetyl-CoA producing enzymes in epigenetic regulation

Inflammation-dependent changes in gene expression programs in innate immune cells, such as macrophages, involve extensive reprogramming of metabolism. This reprogramming is essential for the production of metabolites required for chromatin modifications, such as acetyl-CoA, and regulate their usage...

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Bibliographic Details
Main Authors: Marta Russo, Francesco Pileri, Serena Ghisletti
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1272646/full