Spectroscopic studies on photodegradation of atorvastatin calcium

Abstract In this work, the photodegradation process of atorvastatin calcium (ATC) is reported as depending on: (1) the presence and the absence of excipients in the solid state; (2) the chemical interaction of ATC with phosphate buffer (PB) having pH equal to 7 and 8; and (3) hydrolysis reaction of...

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Bibliographic Details
Main Authors: Madalina Oprica, Miruna Iota, Monica Daescu, Szilard N. Fejer, Catalin Negrila, Mihaela Baibarac
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94693-5