Targeted anti-cancer therapy: Co-delivery of VEGF siRNA and Phenethyl isothiocyanate (PEITC) via cRGD-modified lipid nanoparticles for enhanced anti-angiogenic efficacy

Targeted anti-cancer therapy: Co-delivery of VEGF siRNA and Phenethyl isothiocyanate (PEITC) via cRGD-modified lipid nanoparticles for enhanced anti-angiogenic efficacy

Anti-tumor angiogenesis therapy, targeting the suppression of blood vessel growth in tumors, presents a potent approach in the battle against cancer. Traditional therapies have primarily concentrated on single-target techniques, with a specific emphasis on targeting the vascular endothelial growth f...

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Bibliographic Details
Main Authors: Bao Li, Haoran Niu, Xiaoyun Zhao, Xiaoyu Huang, Yu Ding, Ke Dang, Tianzhi Yang, Yongfeng Chen, Jizhuang Ma, Xiaohong Liu, Keda Zhang, Huichao Xie, Pingtian Ding
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Anti-angiogenesis
Tumor apoptosis
Nanoparticles
VEGF siRNA
Hypoxia inducible factor (HIF)-1 protein
Phenethyl isothiocyanate (PEITC)
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087624000084

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http://www.sciencedirect.com/science/article/pii/S1818087624000084

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