Reverse genetic approaches allowing the characterization of the rabies virus street strain belonging to the SEA4 subclade

Reverse genetic approaches allowing the characterization of the rabies virus street strain belonging to the SEA4 subclade

Abstract Rabies virus (RABV) is the causative agent of rabies, a lethal neurological disease in mammals. RABV strains can be classified into fixed strains (laboratory strains) and street strains (field/clinical strains), which have different properties including cell tropism and neuroinvasiveness. R...

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Bibliographic Details
Main Authors: Nijiho Kawaguchi, Yukari Itakura, Kittiya Intaruck, Takuma Ariizumi, Michiko Harada, Satoshi Inoue, Ken Maeda, Naoto Ito, William W. Hall, Hirofumi Sawa, Yasuko Orba, Michihito Sasaki
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Scientific Reports
Subjects:
Rabies virus
Street strain
Reverse genetics
Viral pathogenicity
Live-cell imaging
Online Access:https://doi.org/10.1038/s41598-024-69613-y

Internet

https://doi.org/10.1038/s41598-024-69613-y

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