Late-Onset Medullary Thyroid Cancer in a Patient with a Germline <i>RET</i> Codon C634R Mutation

Late-Onset Medullary Thyroid Cancer in a Patient with a Germline <i>RET</i> Codon C634R Mutation

<b>Background</b>: Multiple endocrine neoplasia type 2A (MEN2A) is a rare, hereditary syndrome resulting from a germline mutation in the <i>RET</i> proto-oncogene and characterized primarily by medullary thyroid cancer (MTC), pheochromocytoma (PHEO), and hyperparathyroidism....

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Bibliographic Details
Main Authors: Agnieszka Walczyk, Kajetan Zgubieński, Grzegorz Chmielewski, Kinga Hińcza-Nowak, Artur Kowalik, Jarosław Jaskulski, Aldona Kowalska
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Diagnostics
Subjects:
multiple endocrine neoplasia type 2A
hereditary medullary thyroid cancer
germline C634R <i>RET</i> mutation
genotype-phenotype correlation
risk stratification
Online Access:https://www.mdpi.com/2075-4418/11/8/1448

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https://www.mdpi.com/2075-4418/11/8/1448

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