Evolution of Graves’ Disease during Immune Reconstitution following Nonmyeloablative Haploidentical Peripheral Blood Stem Cell Transplantation in a Boy Carrying Germline <i>SAMD9L</i> and <i>FLT3</i> Variants

Evolution of Graves’ Disease during Immune Reconstitution following Nonmyeloablative Haploidentical Peripheral Blood Stem Cell Transplantation in a Boy Carrying Germline <i>SAMD9L</i> and <i>FLT3</i> Variants

Graves’ disease, characterized by hyperthyroidism resulting from loss of immune tolerance to thyroid autoantigens, may be attributable to both genetic and environmental factors. Allogeneic hematopoietic stem cell transplantation (HSCT) represents a means to induce immunotolerance via an artificial i...

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Bibliographic Details
Main Authors: Peng Peng Ip, Li-Hua Fang, Yi-Ling Shen, Kuan-Chiun Tung, Ming-Tsong Lai, Li-Ying Juan, Liuh-Yow Chen, Rong-Long Chen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
<i>FLT3</i> variant
Graves’ disease
HLA-B*46:01
HLA-DRB1*09:01
nonmyeloablative haploidentical peripheral blood stem cell transplantation
<i>SAMD9L</i> variant
Online Access:https://www.mdpi.com/1422-0067/23/16/9494

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https://www.mdpi.com/1422-0067/23/16/9494

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