Generation of H11-albumin-rtTA Transgenic Mice: A Tool for Inducible Gene Expression in the Liver
The modification of the mouse genome by site-specific gene insertion of transgenes and other genetic elements allows the study of gene function in different developmental stages and in the pathogenesis of diseases. Here, we generated a “genomic safe harbor” Hipp11 (H11) locus-specific knock-in trans...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2019-02-01
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Series: | G3: Genes, Genomes, Genetics |
Subjects: | |
Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.118.200963 |