During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.
During establishment of spermatogenesis at the prepubertal age, an early germ cells apoptotic wave occurs likely aimed to remove abnormal germ cells and to maintain a proper cell number ratio between maturating germ cells and Sertoli cells. Here we assessed Sertoli and germ cell apoptosis in relatio...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Via Medica
2008-04-01
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Series: | Folia Histochemica et Cytobiologica |
Online Access: | http://czasopisma.viamedica.pl/fhc/article/view/4489 |