During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.

During establishment of spermatogenesis at the prepubertal age, an early germ cells apoptotic wave occurs likely aimed to remove abnormal germ cells and to maintain a proper cell number ratio between maturating germ cells and Sertoli cells. Here we assessed Sertoli and germ cell apoptosis in relatio...

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Bibliographic Details
Main Authors: Katarzyna Marchlewsk, Jolanta Slowikowska-Hilczer, Renata Walczak-Jedrzejowska, Elzbieta Oszukowska, Krzysztof Kula
Format: Article
Language:English
Published: Via Medica 2008-04-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4489